Discover molecular mechanisms of cell function and response with time course dosing, imaging and molecular readout at single-cell resolution. The future is functional genomics. Polaris represents the seamless integration of cell biology and molecular biology at the single-cell level. It allows for the correlation of the cell’s phenotype, physiological condition, and molecular signature to discover the genetic circuits regulating cell function or compare a population’s sensitivity to environmental changes. Individual cells after selection, are challenged with factors of choice under strict environmental conditions for up to 24 hours and then each cell’s acute response measured transcriptionally via next-generation sequencing.
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