Rare diseases: A public health priority

Rarity is an attribute which finds contextual appreciation or criticism. A rare gem could be an object of utmost desire, but a rare genetic mutation which translates into the rare, incurable disease is not. A disease which shows particularly low prevalence as it affects a small number of individuals in a population classifies as a […]

Super-silenced DNA study hints at new ways to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Celllast week by investigators from the Perelman School of Medicine at the University of Pennsylvania. “In the past, most labs, including my own, […]

Programming DNA to deliver cancer drugs

DNA has an important job — it tells your cells which proteins to make. Now, a research team at the University of Delaware has developed technology to program strands of DNA into switches that turn proteins on and off. UD’s Wilfred Chen Group describes their results in a paper published Monday, March 12 in the […]

Found: A new form of DNA in our cells

It’s DNA, but not as we know it. In a world first, Australian researchers have identified a new DNA structure — called the i-motif — inside cells. A twisted ‘knot’ of DNA, the i-motif has never before been directly seen inside living cells. The new findings, from the Garvan Institute of Medical Research, are published […]