Covaris provides tools and technologies to improve pre-analytical sample preparation, enable novel drug formulations, and manage compounds in the drug discovery process. 

The Covaris technological foundation is based on its proprietary and patented AFA™ technology. AFA enables a vast array of non-contact, isothermal processes to be developed for use in a broad range of applications in Genomics, Proteomics, Cell Biology and Drug Discovery, and Formulation.

ME220 Focused-ultrasonicator

Fully-integrated benchtop sample preparation system based on Adaptive Focused Acoustics® (AFA™) technology. The ME220 Focused-ultrasonicator is the multi-sample, multi-application benchtop sample preparation solution for every lab

Key Features:

  • 1 to 8 sample batch processing at the benchtop
  • The “Scientist’s Standard”in a compact, easy-to-use system, formatted for batch-processing
  • Precise and accurate results with AFA-energetics 
  • Integrated chiller and automated water management
  • Powerful SonoLab software with preloaded protocols
  • The automated water management system provides a 30-day run capacity, making it virtually maintenance-free.

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M220 Focused ultrasonicator

DNA Shearing for next generation sequencing

M220 Focused-ultrasonicator™ is designed for Next-Gen Sequencing applications requiring fragment sizes between 150bp and 5kb. Compact size and ease-of-use make the M220 Focused-ultrasonicator the ideal DNA shearing solution for MiSeq™. Integrated temperature control within the M220 eliminates the need for an external chiller, saving space and cost.

Key Features

  • Proven Covaris AFA shearing process
  • Generates tight, highly reproducible fragment distributions
  • Optimized shearing programs to generate fragment sizes between 150 and 5000 bp.
  • Effective for low-mass, high epitope recovery chromatin shearing

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S220/220X High performance sample preparation system

The S220 Focused-ultrasonicator is a versatile, high power system engineered for pre-analytical sample processing with Covaris' patented Adaptive Focused Acoustics™. Utilizing a spherical acoustic transducer, specifically designed AFA™ Tubes, and advanced electronics, AFA delivers controlled energy precisely and accurately to sample volumes from 25 μl to 10 ml.

Key Features

  • Single-tube sample preparation
  • High recovery and reproducibility
  • Fast and easy to use
  • Broad Applications: Disruption, extraction, dissolution
  • Superior technology

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E220/220X High performance, multi sample preparation system

The E220 enables multi-sample, batch preparation, capable of processing a wide range of sample types and volumes. The E220 may be programed to process from 1 to 96 samples in a single batch. For example, with 96 samples, 96 different AFA energies may be pre-programmed. With the available racks, the E220 instrument is easily configured for use with all AFA Tubes (volumes from 50µl to 10ml) including single AFA microTUBE™ and the AFA 96 microTUBE Plate, for both single and batch sample processing. The E220 can be operated as a stand-alone unit, or easily integrated as part of an automated laboratory system.

Key Features

  • Multi-sample preparation in tubes, strips or microplates 1-96 sample capacity
  • High recovery and reproducibility
  • Broad Applications Disruption, extraction, dissolution
  • Automation ready

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